منابع مشابه
Immunosuppressive drugs and fertility
Immunosuppressive drugs are used in the treatment of inflammatory and autoimmune diseases, as well as in transplantation. Frequently prescribed in young people, these treatments may have deleterious effects on fertility, pregnancy outcomes and the unborn child. This review aims to summarize the main gonadal side effects of immunosuppressants, to detail the effects on fertility and pregnancy of ...
متن کاملImmunosuppressive Drugs and Kidney Post-transplant Diabetes Mellitus
Background: As the rate of renal transplantation increases, more immunosuppressive drugs such as cyclosporine A (CsA) are consumed, particularly during the early months following transplantation, leading to post-transplant diabetes mellitus (PTDM) which can cause death. Objective: The present study examined the role of CsA in causing PTDM and other effect...
متن کاملOral immunosuppressive drugs.
The last few decades have witnessed remarkable achievements in the development of immunosuppressive drugs, made possible by significant advances in molecular immunology and improved understanding of the mechanisms by which cells communicate. The identification of the relevant cells involved in a pathological process is the key to understanding effective immunosuppressive strategies. For example...
متن کاملPharmacodynamic monitoring of immunosuppressive drugs.
Pharmacodynamic (PD) monitoring measures the biological response to a drug, which alone--or coupled with pharmacokinetics--provides a novel method for optimization of drug dosing. PD monitoring has been investigated by us and other investigators primarily for four immunosuppressive drugs: cyclosporine (CsA), azathioprine (AZA), mycophenolate mofetil (MMF), and rapamycin (RAPA). PD monitoring of...
متن کاملAnti-inflammatory and immunosuppressive drugs and reproduction
Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these d...
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ژورنال
عنوان ژورنال: Orphanet Journal of Rare Diseases
سال: 2015
ISSN: 1750-1172
DOI: 10.1186/s13023-015-0332-8